女，1965年生。博士、教授、教研室主任。研究方向：人类生物学。专注细胞生物学，神经生物学。
全日制教育(毕业时间、院校、系及专业)
1983.9-1987.7 河南师范大学 生物系 生物学专业 学士学位
1987.9-1990.7 北京师范大学 细胞生物学专业 硕士学位
2000.12- 2005.7马尔堡大学解剖和细胞研究所 人类生物学专业 博士学位 （德国，马尔堡）
获得奖惩
教学成果
科研业绩 国际会议摘要
1. A. Ji, J. M. Wroblewski, N. R. Webb, D. R. van der Westhuyzen. PLTP Acts in Concert with
SAA to Reduce Plasma HDL Levels in Miceand Modulates Nascent HDL Formation in
Hepatocytes Arteriosclerosis, thrombosis, and Vascular Biology Annual Conference in Chicago,
Illinois, USA on April 28-30, 2012
2. J. Meyer, A. Ji, L. Cai, D. R. van der Westhuyzen. Novel Mechanism of Low-Density
Lipoprotein--Derived Cholesteryl Ester Uptake and Hydrolysis During Macrophage Foam Cell
Formation Arteriosclerosis, thrombosis, and Vascular Biology Annual Conference in Chicago,
Illinois, USA on April 28-30, 2012
3. L. Cai, Z. Wang, J. Meyer, A. Ji, X. Wang, D. R. van der Westhuyzen. SR-BI in Macrophages
Modulate Inflammatory Response to LPS Arteriosclerosis, thrombosis, and Vascular Biology
Annual Conference in Chicago, Illinois, USA on April 28-30, 2011
4. J. Meyer, A. Ji, L. Cai, D. R. van der Westhuyzen. Low-Density Lipoprotein Cholesteryl Esters
Are Taken Up Selectively by Macrophages into a Reversible Pool Arteriosclerosis, thrombosis,
and Vascular Biology Annual Conference in Chicago, Illinois, USA on April 28-30, 2011
5. A. Ji, J. M. Wroblewski, A. Jahangiri, M. C. De Beer, F. C. De Beer, D. R. van der Westhuyzen.
Serum Amyloid A and Endothelial Lipase Decrease ABCA1-dependent HDL Formation by
hepatocytes 6th IAS-Sponsored Workshop on High Density Lipoproteins in Whistler, British
Columbia, Canada on May 17-20, 2010
6. A. Jahangiri, D. R. van der Westhuyzen, M. C. De Beer, J. M. Wroblewski, V. J. Noffsinger, A.
Ji, F. C. De Beer. HDL Remodeling by Serum Amyloid A and Cholesteryl Ester Transfer Protein
in Vivo Enhances ABCA1-dependent Cholesterol Efflux 6th IAS-Sponsored Workshop on High
Density Lipoproteins in Whistler, British Columbia, Canada on May 17-20, 2010
7. A. Ji, L. Cai, M. C. De Beer, J. M. Wroblewski, X. Wang, Z. Wang, D. R. van der Westhuyzen.
HDL Formation by Hepatocytes: Role of ABC Transporters A1, G1, andScavenger Receptor B-I
2010 Arteriosclerosis, thrombosis, and Vascular Biology Annual Conference in San Francisco,
California, USA
科研业绩
8.
J. M. Wroblewski, A. Ji, A. Jahangiri, M. C. De Beer, V. J. Noffsinger, D. R. van der
Westhuyzen, F. C. De Beer. Serum Amyloid A and Endothelial Lipase Decrease HDL Formation
in Mice Both in Vivo and in Vitro 2010 Arteriosclerosis, thrombosis, and Vascular Biology
Annual Conference in San Francisco, California, USA
9. A. Akinmusire, L. Cai, A. Ji, D. R. van der Westhuyzen. Uptake and Intracellular Trafficking of
HDL Apolipoproteins 2010 Arteriosclerosis, thrombosis, and Vascular Biology Annual
Conferencein San Francisco, California, USA
10. L. Cai, Z. Wang, A. Ji, J. Meyer, X. Wang, E. Eckhardt, D. R. van der Westhuyzen. Scavenger
Receptor CD36 Influences Adipocyte Tissue Function 2010 Arteriosclerosis, thrombosis, and
Vascular Biology Annual Conference in San Francisco, California, USA
11. M. C. De Beer, J. M. Wroblewski, A. Jahangiri, A. Ji, D. R. van der Westhuyzen, F. C. De Beer,
N. R. Webb. Cellular Cholesterol Efflux During the Acute Phase 2010 Arteriosclerosis,
thrombosis, and Vascular Biology Annual Conference in San Francisco, California, USA
12. A. Ji, L. Cai, M. C. De Beer, X. Wang, Z. Wang, D. R. van der Westhuyzen. High Density
Lipoprotein remodeling by Scavenger Receptor Class B Type I and Cholesteryl Ester Transfer
Protein and the Effects on Cholesterol Transport 2009 Arteriosclerosis, thrombosis, and Vascular
Biology Annual Conference in Washington, DC, USA
13. A. Ji
, D. R. van der Westhuyzen. SR-BI regulation and function in bone marrow macrophages
Gill Heart Institute Cardiovascular Research Day 2008, Lexsington, KY, USA
14. L. Cai, A. Ji
, Y. Li, X. Wang, T. Liu, J. Meyer, D. R. van der Westhuyzen. The role of HDL
receptor SR-BI and LDL receptor in adrenal steroid hormone synthesis Gill Heart Institute
Cardiovascular Research Day 2008, Lexington, KY, USA
15. A. Ji
, L. Cai, A. Akinmusire, X. Wang, Z. Wang, D. R. van der Westhuyzen. SR-BI dependent
cholesterol efflux in macrophages. 2008 South East Lipid Research Conference, Georgia, USA
16. A. Ji
, L. Cai, X. Wang, Y. Li, A. Akinmusire, D. R. van der Westhuyzen. Aggregated LDL
downregulates macrophage SR-BI expression. Program No. P151. 2008 Arteriosclerosis,
thrombosis, and Vascular Biology Annual Conference in Atlanta, Georgia, USA
17. L. Cai, A. Ji
, Y. Li, S. Shetty, D. R. van der Westhuyzen. The role of HDL receptor SR-BI and
LDL receptor in adrenal steroid hormone synthesis. Program No. P142. 2008 Arteriosclerosis,
thrombosis, and Vascular Biology Annual Conference in Atlanta, Georgia, USA
18. M. C. De Beer, L. Cai, A. Ji
, F. C. De Beer, D. R. van der Westhuyzen. SAA blocks modified
LDL uptake and promotes cellular cholesterol efflux in a CD36-specific manner. PO4-105 76 th
Congress of the European Atherosclerosis SocietyJune 10-13, 2007, Helsinki, Finland
19. L. Cai, M. C. De Beer, A. Ji
, F. C. De Beer, D. R. van der Westhuyzen. SAA promotes CD36
mediated cellular cholesterol efflux Gill Heart Institute Cardiovascular Research Day 2006,
Lexington, KY, USA
20. A. Ji
, Y. Li, M. Peter, E. Weihe, M.K. Schafer. Cell-specific expression of calcitonin receptor
isoforms in hypothalamic neurons regulating feeding behaviour. Program No. 49.17. 2003
Abstract Viewer/Itinerary Planner.Washington, DC, USA: Society for Neuroscience, 2003.
Online.
21. Y. Li; A. Ji
; F. Bender; M. Bette; E. Weihe; M.K.-H. Schafer (2001) Neuronal and
non-neuronal expression of TNF receptors in rat dorsal root ganglion: effects of LPS. Soc
Neurosci Abstr 27:52.2.
科研业绩
22. F.L.P. Bender, M. Mederos y Schnitzler, Y. Li, A. Ji
, E. Weihe, T. Gudermann, M.K. Schafer.
Expression and functional characterization of the vanilloid receptor-like trp channel vrl-1 in the
primary sensory cell line f-11. program no. 48.23. 2002 abstract viewer/itinerary planner.
Washington, DC, USA: Society for Neuroscience, 2002. Online.
23. Y. Li, A. Ji
, M.K. Schafer. Toll-like receptor 4 is expressed by peptidergic presumed nociceptive
neurons in rat dorsal root ganglion Program No. 46.19. 2002 Abstract Viewer/Itinerary Planner.
Washington, DC, USA: Society for Neuroscience, 2002. Online.
学术论文
1. Ailing Ji
, Joanne M. Wroblewski, Nancy R. Webb and Deneys R. van der WesthuyzenImpact of
Phospholipid Transfer Protein on Nascent High-Density Lipoprotein Formation and Remodeling
Arterioscler Thromb Vasc Biol. 2014;34:1910-1916. (SCI, IF 6.338)
2. Jason M. Meyer, Ailing Ji
, Lei Cai , and Deneys R. van der WesthuyzenMinimally oxidized
LDL inhibits macrophage selective cholesteryl ester uptake and native LDL-induced foam cell
formationJ. Lipid Res . 2014. 55: 1648–1656. (并列第一作者)
3. Maria C. De Beer, Joanne M. Wroblewski, Victoria P. Noffsinger, Debra L. Rateri, Deborah A.
Howatt, Anju Balakrishnan, Ailing Ji
, Preetha Shridas, Joel C. Thompson, Deneys R. van der
Westhuyzen, Lisa R. Tannock, Alan Daugherty, Nancy R. Webb and Frederick C. De Beer
Deficiency of Endogenous Acute Phase Serum Amyloid A Does Not Affect Atherosclerotic
Lesions in Apolipoprotein E-Deficient MiceArterioscler Thromb Vasc Biol.
2014;34:255-261(SCI, IF 6.338)
4. Maria C. de Beer, Joanne M. Wroblewski, Victoria P. Noffsinger, Ailing Ji,
Jason M. Meyer,
Deneys R. van der Westhuyzen, Frederick C. de Beer, and Nancy R. Webb The Impairment of
Macrophage-to-Feces Reverse Cholesterol Transport during Inflammation Does Not Depend on
Serum Amyloid AJ Lipids. 2013; 2013: 283486
5. Ji A,
Wroblewski JM, Cai L, de Beer MC
, Webb NR, van der Westhuyzen DR. Nascent HDL
formation in hepatocytes and role of ABCA1, ABCG1 and SR-BIJ Lipid Research 2012,
53(3):446-55.(SCI, IF 5.559)
6. Meyer JM, Ji A
, Cai L, van der Westhuyzen DR. High-capacity selective uptake of cholesteryl
ester from native LDL during macrophage foam cell formationJ Lipid Research 2012,
Oct;53(10):2081-91.(SCI, IF 5.559)
7. Cai L, Wang Z, Ji A
, Meyer JM, van der Westhuyzen DR. Scavenger Receptor CD36 Expression
Contributes to Adipose Tissue Inflammation and Cell Death in Diet-Induced Obesity. PLoS ONE
2012, 7(5): e36785. doi:10.1371/journal.pone.0036785. (SCI, IF 4.411)
8. L. Cai, Z. Wang, J. Meyer, A. Ji
, D. R. van der Westhuyzen. Macrophage SR-BI regulates
LPS-induced pro-inflammatory signaling in mice and isolated macrophages J Lipid Research
2012, Aug;53(8):1472-81. (SCI, IF 5.559)
9. A. Ji, J. Meyer, L. Cai, A. Akinmusire, M. C. De Beer, N. R. Webb, D. R. van der
Westhuyzen. Scavenger Receptor SR-BI in Macrophage Lipid Metabolism Atherosclerosis 2011,
217(1):106-12. (SCI, IF 3.794)
10. Wroblewski JM, Jahangiri A, Ji A, de Beer FC, van der Westhuyzen DR, Webb NR. Nascent
HDL formation by hepatocytes is reducedby the concerted action of serum amyloid A and
endothelial lipase. J Lipid Research 2011, 52(12):2255-61. (SCI, IF 5.559)
11. De Beer MC, Ji A, Jahangiri A, Vaughan AM, De Beer FC, Van der Westhuyzen DR, Webb
NR. ATP binding cassette G1-dependent cholesterol efflux during inflammation. J Lipid Research
2011, 52(2):345-53. (SCI, IF 5.559)
科研
业绩 13. De Beer MC, Webb NR, Wroblewski JM, Noffsinger VP, Rateri DL, Ji A, Van Der
Westhuyzen DR, De Beer FC. Impact of serum amyloid A on high density lipoprotein
composition and levels. J Lipid Research 2010, 51(11):3117-25. (SCI, IF 5.559)
14. 吉爱玲
, 封青川，毕彩霞，徐存栓 （2001）HSP 70 单克隆抗体的制备. 动物学报，47(专刊):
247-249
15. 徐存栓， 李永辉，段瑞峰，卢爱灵，夏民，吉爱玲
(2001) 短间隔连续部分肝切除对大鼠
生存和肝组织结构的影响. 动物学报 47(6), 659-665.
16. 李效宇, 夏民, 李莉, 卜艳珍, 吉爱玲
, 姬生栋, 徐存栓 (2000) 金鱼不同组织器官及胚胎发
育不同时期蛋白水解酶的种类和活性变化. 水生生物学报 24 (2), 128-136.
17. 胡轶红, 吉爱玲
, 徐存栓 (2000) 大鼠八种器官的蛋白质图谱分析. 河南科学 18(1), 59-62.
18. 姬生栋，李金亭，吉爱玲
， 李吉学，王丹，徐存栓 (2000) 小麦生育前期 POD 同工酶的
动态变化 (2000) 广西植物 20(4), 361-366.
19. 吉爱玲
, 李彦章, 向华, 伍雁, 封青川, 徐存栓 (1999) 猕猴消化系统各器官蛋白水解酶种
类和性质研究. 解剖学报 30(3), 230-236.
20. 李彦章, 吉爱玲
., 夏民, 姬生栋,伍雁, 杨春玲, 封青川 徐存栓 (1999) 猕猴神经系统各器
官蛋白水解酶种类和性质研究. 动物学杂志 33(6), 31-34.
21. 吉爱玲
, 胡轶红, 封青川, 李效阳, 卢爱玲, 徐存拴 (1999) 大白鼠热休克反应中HSP70 的
表达动态分析. 中国动物科学研究 823-826 中国动物学会编, 中国林业出版社.
22. 吉爱玲
, 杨保胜, 向华, 李效阳, 孙璐, 徐存拴 (1999) 复方肿瘤血管生成抑制因子口服液
对小鼠免疫功能的影响. 河南师范大学学报 (自然科学版) 27(1), 64-68.
23. 徐存拴, 李腊月, 吉爱玲
, 向华, 石金保, 李全富, 杨保胜 (1999) 复方肿瘤血管生成抑制
因子口服液与化疗药物合用对小鼠 Ehrlich腹水癌的抑制作用研究. 河南师范大学学报 (自然科学
版) 27(1), 60-63.
24. 姬生栋, 夏民, 吉爱玲
, 李吉学, 王丹, 李庚午 (1999) 不同基因型小麦叶片气孔超微结构观
察 中国医学物理学杂志 16(5), 98-99.
25. 姬生栋, 吉爱玲
, 夏民, 李吉学, 李庚午 (1999) 三种春化类型小麦叶片的扫描电镜观察 中
国医学物理学杂志 16(5), 100-102.
26. 徐存栓, 吉爱玲
, 夏民, 常蕴华, 伍雁, 赵绪永 (1998) 用复性电泳技术研究溶酶体蛋白水
解酶的性质和活性. 河南科学 16(2), 185-192.
27. 吉爱玲, 赵晓进, 李彦章, 伍雁, 杨春玲, 封青川, 徐存栓 (1998) 猕猴生殖, 泌尿, 免疫系
统各器官蛋白水解酶种类和性质. 解剖学报 29(2), 195-199.
28. 徐存栓, 吉爱玲, 夏民, 李彦章, 向华. (1998). C6大白鼠神经胶质瘤细胞HSP68 的修饰和降
解分析. 生物化学与生物物理学报 30(2),179-184.
29. Guangchang Pang, Dongxu Zhao, Xinlin Yang, Guangwen Chen, Ailing Ji (1998) A New
Technique of Micro-protein-electrophoresis and Ultrasensitive Staining. Developmental and Reproductive
Biology 7(1), 81-89.
30. 吉爱玲, 赵晓进, 李彦章, 伍雁, 杨春玲, 封青川, 徐存栓 (1998) 猕猴生殖, 泌尿, 免疫系
统各器官蛋白水解酶种类和性质. 解剖学报 29(2), 195-199.
31. 徐存栓, 吉爱玲, 夏民, 李彦章, 向华. (1998). C6大白鼠神经胶质瘤细胞HSP68 的修饰和降
解分析. 生物化学与生物物理学报 30(2),179-184.
32. Guangchang Pang, Dongxu Zhao, Xinlin Yang, Guangwen Chen, Ailing Ji (1998) A New
Technique of Micro-protein-electrophoresis and Ultrasensitive Staining. Developmental and
Reproductive Biology 7(1), 81-89
33. 姬生栋, 夏民, 吉爱玲
, 胡轶红, 王丹, 徐存栓 (1997) 不同基因型小麦籽粒生育期蛋白质的
动态变化. 河南师范大学学报 25(4), 75-78
34. 吉爱玲
, 李华, 杨晓红, 柳惠图 (1992) 6m2 细胞转化与肌醇磷脂代谢相关性研究. 生物化
学杂志 8(4), 390-394.
科研
业绩 GenBank Accession Number
1. A. Ji
, Li,Y., Bender,F.L.P. and Schafer,M.K.H. (2003) F-11 rat/mouse fusion cell line TRPV2
protein mRNA, complete cds. GenBank AY487844
2. Y. Li, A. Ji
, M. K. Schafer (2002) Rattus norvegicus TNFR2 mRNA, transcript variant 1,
AF498039; transcript variant 2, AY191268; transcript variant 3, AY191269
3. Y. Li, A. Ji
, M. K. Schafer (2002) Rattus norvegicus toll likereceptor 2 mRNA, transcript variant
1, AY151255; transcript variant 2, AY151256
4. Y. Li, A. Ji
, M. K. Schafer (2002) Rattus norvegicus toll like receptor 9 mRNA, complete cds.
GenBank AY191271.
5. Y. Li, A. Ji
, M. K. Schafer (2002) Rattus norvegicus myeloid differentiation primary response
gene 88 (MyD88), complete cds. GenBank AY191270
6. Y. Li, A. Ji
, M. K. Schafer (2001) Rattus norvegicus CGRP-receptor component protein mRNA,
complete cds. GenBank AF440799.
Award
2010 HDL Workshop Travel Awards for Young Investigators
6 th IAS-Sponsored Workshop on High Density Lipoproteins in Whistler, British Columbia, Canada
on May 17-20, 2010
高等院校教材
现代细胞生物学技术, 副主编，青岛海洋大学出版社 1995 年
现代细胞遗传学, 编委，河南科技出版社 1994 年
参加科研项目
1. National Institutes of Health (NIH) Program Project Grant PO1 HL086670 to D. R. van der
Westhuyzen (PI) 04/01/07-03/30/12, total $ 5,065,000 USA
HDL Function and Metabolism During Inflammation
2. National Institutes of Health (NIH) R01 HL063763 to D.R. van der Westhuyzen (PI) 08/01/05 –
07/31/09, total $1,125,000 USA
SR-BI and SR-BII Recycling and Selective Lipid Uptake
3. Bundesministerium für Bildung und Forschung (BMBF) 01GS01118，德国教育科技部项目，
2000-2004，100万欧元
4. 热休克诱导的 65KDaATP 结合蛋白酶基因的分离， 国家自然科学基金 39670372， 1996-1999，
第二完成人
5. 蛋白酶体在热休克反应中的作用，河南省科委 964021900， 0.5 万元，1996-1998，主持人
6. 基因工程人 D 型干扰素生产工艺研究，河南省教育厅 96180013，0.5 万元， 1996-1999，
第三完成人
7. 肝再生过程中蛋白酶与 HSP 动态变化及肝功能调节中的作用， 河南省教育厅 96180017， 0.5
万元， 1996-1999，第三完成人
8. 热休克蛋白调节小麦生长发育的分子机制研究，河南省科委 974013100，0.5 万元，
1997-1999，第三完成人
9. 麦田杂草蛋白水解酶谱分析及新型除草剂研究，98180012，1.5 万元， 1998-2000，第四完
成人
科学技术成果鉴定
复方肿瘤血管生成抑制因子口服液抗肿瘤作用研究，河南省科委, 豫科鉴委字 (1998) 第108 号，第五完成人。